Interested Article - Трансглутаминаза кератиноцитов

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? ??????????? ?????????????????? ???????????? ??????????????? ???????? ???????? ????? ??????????? ????????? ???????? ???????????? ?????????? ???????????, ?? ?????? ???? (???????? 15 ??) ?? ????? ????????? ???????? , ??????????? ??? ?????? ????????????? ?????? . ?????????? ???????? ???????? ?????? ??????????? ????? ????????????? ???????? ???? ????????? ?????????????? ????????????? ??????, ???????????? ?????????? ?/??? ?????????? ??????????? ??????. ??????? ?????????? ?????????????? ?????????? ????? ??? (5-10 %) ????????? ? ???????? ?????????????????? ??????? ????? ??????, ??? ????????? ????????? ???????????? ????????, ??????????? ??? ?????? ???????????????? ??????????? ????????? ????????.

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???????????? ??????? ???????????????? ????????????? (???) ?????? ? ??????, ??? ? ?????, ?????????? ??????????? ????????, ??????????? ???????????? ??????? ?????????? ??????? ???????? . ??? ?????? ?????, ??? ? ??????? ??????????? ???????? ?????????? ???????? ? ?????????? ?????????? ?????????? ???????????? ????????????? ???? ???. ???? ?????????? ????? ?????????? ???????????????? ???????? ???? TGM1, ??????? ?????????? ? ???? ????????? ?????????, ???????????? ? ?????? 14q11 ?? 14-? ?????????, ??? ???? ???????? ? ???? ????????? ????????????. ????? ??????? ????? ????????? ?????????????? ??? ???????????? ????????????, ??? ????????? ? ?????????? ???????????? ??????? ? ?????????? ??????????? ???????? ??????????? ????????? ????????.

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? - Ensembl , May 2017
? - Ensembl , May 2017
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Grenard P, Bates MK, Aeschlimann D (August 2001). "Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z". The Journal of Biological Chemistry . 276 (35): 33066—78. doi : . PMID .
.
(????.) . ???? ?????????: 18 ?????? 2023. 18 ?????? 2023 ????.
? Eckert RL, Sturniolo MT, Broome AM, Ruse M, Rorke EA (March 2005). . The Journal of Investigative Dermatology . 124 (3): 481—92. doi : . PMID .
? Huber M, Rettler I, Bernasconi K, Frenk E, Lavrijsen SP, Ponec M, et al. (January 1995). "Mutations of keratinocyte transglutaminase in lamellar ichthyosis". Science . 267 (5197): 525—8. Bibcode : . doi : . PMID . S2CID .
Kim SY, Jeitner TM, Steinert PM (January 2002). "Transglutaminases in disease". Neurochemistry International . 40 (1): 85—103. doi : . PMID . S2CID .
Hennies HC, Küster W, Wiebe V, Krebsová A, Reis A (May 1998). . American Journal of Human Genetics . 62 (5): 1052—61. doi : . PMC . PMID .

[refGRCh38EnsemblENSG00000092295,_ENSG00000285348-1] ? - Ensembl , May 2017

[refGRCm38EnsemblENSMUSG00000022218-2] ? - Ensembl , May 2017

[3] ???????????? ????? ?????????????????? ??????????, ???????????? ??????????? ?????????? ??? .

[4] ???????????? ????? ?????????????????? ??????????, ???????????? ??????????? ?????????? ??? .

[pmid11390390-5] Grenard P, Bates MK, Aeschlimann D (August 2001). "Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z". The Journal of Biological Chemistry . 276 (35): 33066—78. doi : . PMID .

[entrez-6] .

[UniProt-7] (????.) . ???? ?????????: 18 ?????? 2023. 18 ?????? 2023 ????.

[pmid15737187-8] ? Eckert RL, Sturniolo MT, Broome AM, Ruse M, Rorke EA (March 2005). . The Journal of Investigative Dermatology . 124 (3): 481—92. doi : . PMID .

[Huber_1995-9] ? Huber M, Rettler I, Bernasconi K, Frenk E, Lavrijsen SP, Ponec M, et al. (January 1995). "Mutations of keratinocyte transglutaminase in lamellar ichthyosis". Science . 267 (5197): 525—8. Bibcode : . doi : . PMID . S2CID .

[10] Kim SY, Jeitner TM, Steinert PM (January 2002). "Transglutaminases in disease". Neurochemistry International . 40 (1): 85—103. doi : . PMID . S2CID .

[11] Hennies HC, Küster W, Wiebe V, Krebsová A, Reis A (May 1998). . American Journal of Human Genetics . 62 (5): 1052—61. doi : . PMC . PMID .

Interested Article - Трансглутаминаза кератиноцитов

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