Interested Article - MST1R
doriana
- 2020-12-02
- 1
MST1R ( ????. Macrophage-stimulating protein receptor; CD136 ; ?? 2.7.10.1) — ?????????? ????? , ??????????? ????????????? , ??????? ???? ???????? MST1R .
???????
MST1R — ??????????? ????????????? , ??????????? ?????? ?? ????????????? ???????? ? ????????? ?????????? ??? ?????????? ? ???????? . ???????? MST1R ?????????? ?????? ??????????????? ????????, ??????? ????????? ??????, ?? ???????? ? ???????????????. ?????????? ??????? ?? ????????? ??????????? ?????????? ???????????????????? ???????????????? ?????? ?????????, ?? ??????? ??????????? ??????? ?????????? ??????????? ?????????? ??????. ????? ????????? ????????? ? ???? ?????????? ? ???????? ???????? ??????????????? ? ????????????? PI3-?????? , ??? ? ?????????? ?????? . ?????????????? ???? ?????????? ?????????? ????????? ?????????? ?????, ??????? RAS-ERK, ?????????????-3-?????? AKT1 ? PLC-?????-PKC. ?????????? MST1R ?????????? ??????? ?????????? ?? ???? ???????? ???????? ? ???????????? ????????????? ??????, ? ????? ?? ????????? ?? ???????????? ???????. ????? ?????, MST1R ?????? ???? ?? ?????????? ???????? ??????, ????????? ???????? ? ???????????? ?????????? ?????????? . ???????? ????? ????? ????????? ???????, ??????? ????????? ???????? ? ????????????, ? ????? ?? ????????? ??????, ????? ??????? MST1, ??????? ????? .
?????????
MST1R ??????? ?? 1 400 ??????????? , ???????????? ????? 152,2 ???.
??????????????
MST1R ??????????? ? .
??????????
- ? - Ensembl , May 2017
- ? - Ensembl , May 2017
- ???????????? ????? ?????????????????? ??????????, ???????????? ??????????? ?????????? ??? .
- ???????????? ????? ?????????????????? ??????????, ???????????? ??????????? ?????????? ??? .
- Ronsin C, Muscatelli F, Mattei MG, Breathnach R (May 1993). . Oncogene . 8 (5): 1195—202. PMID .
- . ???? ?????????: 17 ??????? 2021. 5 ??????? 2010 ????.
-
Wang MH, Ronsin C, Gesnel MC, Coupey L, Skeel A, Leonard EJ; et al. (1994).
.
Science
.
266
(5182): 117—9.
doi
:
.
PMID
.
{{ cite journal }}: ?????????:???????????? CS1 (????????????? ?????: authors list) ( ?????? ) -
Nanney LB, Skeel A, Luan J, Polis S, Richmond A, Wang MH; et al. (1998).
.
J Invest Dermatol
.
111
(4): 573—81.
doi
:
.
PMID
.
{{ cite journal }}: ?????????:???????????? CS1 (????????????? ?????: authors list) ( ?????? ) -
Feres KJ, Ischenko I, Hayman MJ (2009).
.
Oncogene
.
28
(2): 279—88.
doi
:
.
PMC
.
PMID
.
{{ cite journal }}: ?????????:???????????? CS1 (????????????? ?????: authors list) ( ?????? ) - Li BQ, Wang MH, Kung HF, Ronsin C, Breathnach R, Leonard EJ, Kamata T (November 1995). . Biochem. Biophys. Res. Commun . 216 (1): 110—8. doi : . PMID .
- Iwama A, Yamaguchi N, Suda T (November 1996). . EMBO J . 15 (21): 5866—75. doi : . PMC . PMID .
??????????
- Li BQ, Wang MH, Kung HF, et al. (1995). . Biochem. Biophys. Res. Commun . 216 (1): 110—8. doi : . PMID .
- Wang MH, Ronsin C, Gesnel MC, et al. (1994). "Identification of the ron gene product as the receptor for the human macrophage stimulating protein". Science . 266 (5182): 117—9. doi : . PMID .
- Gaudino G, Follenzi A, Naldini L, et al. (1994). . EMBO J . 13 (15): 3524—32. doi : . PMC . PMID .
- Lee ST, Strunk KM, Spritz RA (1993). . Oncogene . 8 (12): 3403—10. PMID .
- Collesi C, Santoro MM, Gaudino G, Comoglio PM (1996). . Mol. Cell. Biol . 16 (10): 5518—26. doi : . PMC . PMID .
- Bonaldo MF, Lennon G, Soares MB (1997). . Genome Res . 6 (9): 791—806. doi : . PMID .
- Iwama A, Yamaguchi N, Suda T (1997). . EMBO J . 15 (21): 5866—75. doi : . PMC . PMID .
- Sakamoto O, Iwama A, Amitani R, et al. (1997). . J. Clin. Invest . 99 (4): 701—9. doi : . PMC . PMID .
- Follenzi A, Bakovic S, Gual P, et al. (2000). . Oncogene . 19 (27): 3041—9. doi : . PMID .
- Chen YQ, Zhou YQ, Fisher JH, Wang MH (2002). . Oncogene . 21 (41): 6382—6. doi : . PMID .
- Chen YQ, Zhou YQ, Fu LH, et al. (2002). . Carcinogenesis . 23 (11): 1811—9. doi : . PMID .
- Zhou YQ, He C, Chen YQ, et al. (2003). . Oncogene . 22 (2): 186—97. doi : . PMID .
- Danilkovitch-Miagkova A, Duh FM, Kuzmin I, et al. (2003). . Proc. Natl. Acad. Sci. U.S.A . 100 (8): 4580—5. doi : . PMC . PMID .
- Rampino T, Gregorini M, Soccio G, et al. (2003). . Am. J. Surg. Pathol . 27 (6): 779—85. doi : . PMID . S2CID .
- Penengo L, Rubin C, Yarden Y, Gaudino G (2003). . Oncogene . 22 (24): 3669—79. doi : . PMID .
- Maggiora P, Lorenzato A, Fracchioli S, et al. (2003). "The RON and MET oncogenes are co-expressed in human ovarian carcinomas and cooperate in activating invasiveness". Exp. Cell Res . 288 (2): 382—9. doi : . PMID .
- Santoro MM, Gaudino G, Marchisio PC (2003). "The MSP receptor regulates alpha6beta4 and alpha3beta1 integrins via 14-3-3 proteins in keratinocyte migration". Dev. Cell . 5 (2): 257—71. doi : . PMID .
- Angeloni D, Danilkovitch-Miagkova A, Miagkov A, et al. (2004). . J. Biol. Chem . 279 (5): 3726—32. doi : . PMID .
- van den Akker E, van Dijk T, Parren-van Amelsvoort M, et al. (2004). "Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors". Blood . 103 (12): 4457—65. doi : . PMID .
- Raeppel S, Gaudette G, et al. (2010). "Identification of a novel series of potent RON receptor tyrosine kinase inhibitors". Bioorg. Med. Chem. Lett . 20 (9): 2745—9. doi : . PMID .
| 1-50 |
|
|---|---|
| 51-100 |
|
| 101-150 | |
| 151-200 | |
| 201-250 | |
| 251-300 | |
| 301-350 | |
| 351-400 | |
doriana
- 2020-12-02
- 1
