Гуанидин нуклеотид связывающая субъединица бета-2
(
англ.
Guanine nucleotide-binding protein subunit beta-2-like 1
) также известная как
Рецептор для активаци C 1
или
RACK1
(
англ.
Receptor for activated C kinase
) —
белок
массой 32
кДа
, кодируемый у человека
геном
GNB2L1
.
Yarwood, S J; Steele M R; Scotland G; Houslay M D; Bolger G B.
The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform
(англ.)
//
J. Biol. Chem.
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vol. 274
,
no. 21
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P. 14909—14917
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ISSN
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Steele, M R; McCahill A; Thompson D S; MacKenzie C; Isaacs N W; Houslay M D; Bolger G B.
Identification of a surface on the beta-propeller protein RACK1 that interacts with the cAMP-specific phosphodiesterase PDE4D5
(англ.)
//
(англ.)
(
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vol. 13
,
no. 7
). —
P. 507—513
. —
ISSN
. —
doi
:
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↑
Usacheva, Anna; Tian Xinyong; Sandoval Raudel; Salvi Debra; Levy David; Colamonici Oscar R.
The WD motif-containing protein RACK-1 functions as a scaffold protein within the type I IFN receptor-signaling complex
(англ.)
//
(англ.)
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vol. 171
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P. 2989—2994
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↑
Usacheva, A; Smith R; Minshall R; Baida G; Seng S; Croze E; Colamonici O.
The WD motif-containing protein receptor for activated protein kinase C (RACK1) is required for recruitment and activation of signal transducer and activator of transcription 1 through the type I interferon receptor
(англ.)
//
J. Biol. Chem.
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P. 22948—22953
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Chang, B Y; Conroy K B; Machleder E M; Cartwright C A.
RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells
(англ.)
//
(англ.)
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P. 3245—3256
. —
ISSN
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Rigas, Anastasia C; Ozanne Daniel M; Neal David E; Robson Craig N.
The scaffolding protein RACK1 interacts with androgen receptor and promotes cross-talk through a protein kinase C signaling pathway
(англ.)
//
J. Biol. Chem.
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P. 46087—46093
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Wang, Wei; Huang Yan, Zhou Zongxiang, Tang Rong, Zhao Wei, Zeng Li, Xu Ming, Cheng Chao, Gu Shaohua, Ying Kang, Xie Yi, Mao Yumin.
Identification and characterization of AGTRAP, a human homolog of murine Angiotensin II Receptor-Associated Protein (Agtrap)
(англ.)
//
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P. 93—102
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Yaka, Rami; He Dao-Yao; Phamluong Khanhky; Ron Dorit.
Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1
(англ.)
//
J. Biol. Chem.
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P. 9630—9638
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Diederichs, Sven; Bäumer Nicole, Ji Ping, Metzelder Stephan K., Idos Gregory E., Cauvet Thomas, Wang Wenbing, Möller Maria, Pierschalski Sarah, Gromoll Jörg, Schrader Mark G., Koeffler H Phillip, Berdel Wolfgang E., Serve Hubert, Müller-Tidow Carsten.
Identification of interaction partners and substrates of the cyclin A1-CDK2 complex
(англ.)
//
J. Biol. Chem.
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P. 33727—33741
. —
ISSN
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Croze, E; Usacheva A; Asarnow D; Minshall R D; Perez H D; Colamonici O.
Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type I IFN receptor
(англ.)
//
(англ.)
(
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vol. 165
,
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P. 5127—5132
. —
ISSN
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doi
:
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Liedtke, Carole M; Yun C H Chris; Kyle Nicole; Wang Dandan.
Protein kinase C epsilon-dependent regulation of cystic fibrosis transmembrane regulator involves binding to a receptor for activated C kinase (RACK1) and RACK1 binding to Na+/H+ exchange regulatory factor
(англ.)
//
J. Biol. Chem.
: journal. — United States, 2002. — June (
vol. 277
,
no. 25
). —
P. 22925—22933
. —
ISSN
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doi
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Ozaki, Toshinori; Watanabe Ken-ichi; Nakagawa Takahito; Miyazaki Kou; Takahashi Masato; Nakagawara Akira.
Function of p73, not of p53, is inhibited by the physical interaction with RACK1 and its inhibitory effect is counteracted by pRB
(англ.)
//
(англ.)
(
: journal. — England, 2003. — May (
vol. 22
,
no. 21
). —
P. 3231—3242
. —
ISSN
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doi
:
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Koehler, J A; Moran M F.
RACK1, a protein kinase C scaffolding protein, interacts with the PH domain of p120GAP
(англ.)
//
(англ.)
(
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vol. 283
,
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P. 888—895
. —
ISSN
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doi
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Ron, D; Jiang Z; Yao L; Vagts A; Diamond I; Gordon A.
Coordinated movement of RACK1 with activated betaIIPKC
(англ.)
//
J. Biol. Chem.
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P. 27039—27046
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Battle, Michele A; Maher Veronica M; McCormick J Justin.
ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways
(англ.)
// Biochemistry : journal. — United States, 2003. — June (
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Hellberg, Carina B; Burden-Gulley Susan M., Pietz Gregory E., Brady-Kalnay Susann M.
Expression of the receptor protein-tyrosine phosphatase, PTPmu, restores E-cadherin-dependent adhesion in human prostate carcinoma cells
(англ.)
//
J. Biol. Chem.
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doi
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Mourton, T; Hellberg C B; Burden-Gulley S M; Hinman J; Rhee A; Brady-Kalnay S M.
The PTPmu protein-tyrosine phosphatase binds and recruits the scaffolding protein RACK1 to cell-cell contacts
(англ.)
//
J. Biol. Chem.
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vol. 276
,
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P. 14896—14901
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doi
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Ceci, Marcello; Gaviraghi Cristina; Gorrini Chiara; Sala Leonardo A; Offenhäuser Nina; Marchisio Pier Carlo; Biffo Stefano.
Release of eIF6 (p27BBP) from the 1960s subunit allows 1980s ribosome assembly
(англ.)
//
Nature
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Edelmann, Mariola J; Iphöfer Alexander, Akutsu Masato, Altun Mikael, di Gleria Katalin, Kramer Holger B., Fiebiger Edda, Dhe-Paganon Sirano, Kessler Benedikt M.
Structural basis and specificity of human otubain 1-mediated deubiquitination
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//
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P. 379—390
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Liliental, J; Chang D D.
Rack1, a receptor for activated protein kinase C, interacts with integrin beta subunit
(англ.)
//
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Lee, H-S; Millward-Sadler S J; Wright M O; Nuki G; Al-Jamal R; Salter D M.
Activation of Integrin-RACK1/PKCalpha signalling in human articular chondrocyte mechanotransduction
(англ.)
//
(англ.)
(
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P. 890—897
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Литература
Liu Y.V., Semenza G.L.
RACK1 vs. HSP90: competition for HIF-1 alpha degradation vs. stabilization.
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p65 fragments, homologous to the C2 region of protein kinase C, bind to the intracellular receptors for protein kinase C.
(англ.)
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RACK1, a receptor for activated C kinase and a homolog of the beta subunit of G proteins, inhibits activity of src tyrosine kinases and growth of NIH 3T3 cells
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(англ.)
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Intracellular receptors for activated C-kinase in the postmortem human brain: no alteration in Alzheimer disease
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The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform
(англ.)
//
J. Biol. Chem.
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Coordinated movement of RACK1 with activated betaIIPKC
(англ.)
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Receptor for activated C-kinase (RACK-1), a WD motif-containing protein, specifically associates with the human type I IFN receptor
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